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pentobarbital will minimize the level or effect of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.Watch Carefully (1)pentobarbital will minimize the extent or effect of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Lack of, or diminished respons